Endocrine Abstracts

During the past year and a half during the Covid pandemic it has been noted that cases of abnormal thyroid functions post Covid infection rises and few case report published related to thyroiditis. For this we want to present one of our own patient who had Covid 19 infection in January 2020 with good recovery and after that she had symptoms of hyperthyroidism including palpitation weight loss and heat intolerance. It was confirmed with undetectable TSH and high T4 of 30. She w...

Langerhans cell Histiocytosis is a rare neoplastic histiocytic disorder. It has broad spectrum of clinical presentations from single system to multi system. It mainly affects children but can occur in adults. It can present with skin lesions, skull/jaw tumours, polyuria/polydipsia, fever, cough and dyspnea, bone pain, ataxia etc. 25% of adult cases involve Pituitary (anterior and posterior pituitary gland) and hypothalamus. BRAF and MAP2K1 mutations are most ...

Section 1: Case history: A 51-year-old lady was referred to our endocrinology clinic with a 6-month history of palpitations, generalized muscle aches, heat intolerance, increased sweating and significant unintentional weight loss. She is normally fit and well without any significant past medical problem. Her thyroid function tests showed thyrotoxicosis picture with TSH < 0.05 miu/L, Free T4 76pmol/l, Free T3 > 30.8 pmol/l with positive TSH receptor antibodies ( 34.9U/L...

Introduction: Autoimmune thyroiditis can occasionally be associated with a transient hyperthyroid phase which is followed by a hypothyroid state. Thyrotoxicosis is thought to be caused by thyroid cell destruction with release of preformed thyroid hormones into the circulation.Case: An 18-year-old Asian male was admitted to hospital 7with a four week history of lethargy, weight loss, palpitations and excessive sweating. He had tachycardia, sweating, tremo...

Thyroid storm is a rarely seen complication of Thyrotoxicosis complicated by multiple organ dysfunctions. Early recognition is crucial in reducing morbidity and mortality. We present the case of a young lady admitted with traumatic fracture of Tibia and Fibula. She was noted to be in rapid AF and on examination manifested signs of Thyrotoxicosis with palpable goitre. She was noted to be hyperthermic and emotionally labile and confused with signs of right heart failure.Investig...

Case history: A 55-year-old man presented to the Emergency Department with worsening breathlessness 11 days after testing positive for severe acute respiratory syndrome coronavirus 2 (SARS CoV 2). He reported ongoing diarrhoea, starting 1 week prior to the SARS CoV 2 infection. He was previously fit and well, on no regular medication. On examination he was alert, with all clinical observations within normal limits and there were no significant findings in the chest and abdomen...

Introduction: Adrenal insufficiency is characterized by inadequate ¬glucocorticoid production owing to destruction of the adrenal cortex or lack of adrenocorticotropic hormone stimulation. Patients can present with an insidious onset of symptoms, or acutely in adrenal crisis, which requires prompt recognition and treatment. Chronic glucocorticoid therapy is the most common cause of adrenal insufficiency. We present a case with an adrenal insufficiency caused by Itraconazo...

Case history: A 55-year-old man presented to the Emergency Department with worsening breathlessness 11 days after testing positive for severe acute respiratory syndrome coronavirus 2 (SARS CoV 2). He reported ongoing diarrhoea, starting 1 week prior to the SARS CoV 2 infection. He was previously fit and well, on no regular medication. All clinical observations within normal limits and there were no significant examination findings.Results and treatment: ...

It is very rare to have Pituitary metastasis in Renal Cell cancer (RCC). Prevalence of Pituitary metastasis varies from 1-4% in all cancers and about 2.6% in RCC. Most common cancers with pituitary metastasis are breast (33%) and lung (36%). We present a rare case of RCC with pituitary Metastasis presented with severe Hyponatraemia. A 71 years old male with history of renal cell cancer who underwent Right nephrectomy in 2017. He was found to have intrathoracic metastases in 20...

Apraxia of lid opening is defined as non-paralytic motor abnormality characterized by difficulty in lid opening after lid closure.A 10-year-old presented to the ophthalmologist with history delayed opening the right eye after blinking. There was slight delay in opening of right eye after a blink during examination. There was no lid retraction. Visual acuity was normal in both eyes. Initial work up showed normal full blood count, urea and electrolytes and...